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課程資訊 |
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課程名稱 |
分子遺傳學 Molecular Genetics | ||||||||||||
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開課學期 |
108-2 | ||||||||||||
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授課對象 |
生命科學院 生化科技研究所 | ||||||||||||
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授課教師 |
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課號 |
Agron5075 | ||||||||||||
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課程識別碼 |
621 U5300 | ||||||||||||
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班次 |
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學分 |
3.0 | ||||||||||||
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全/半年 |
半年 | ||||||||||||
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必/選修 |
必修 | ||||||||||||
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上課時間 |
星期二7,8,9(14:20~17:20) | ||||||||||||
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上課地點 |
農藝304 | ||||||||||||
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備註 |
碩士班A群組必修10學分課程之一。 總人數上限：20人 | ||||||||||||
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1082Agron5075 | ||||||||||||
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 | ||||||||||||
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課程大綱
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課程概述 |
Genetics is a form of information science. Molecular genetics seeks to understand the rules that govern the transmission of genetic information at the level from DNA to gene action within and between cells (Griffth et al. 2015). In other word, the field of molecular genetics includes how genetic information is organized, replicated, expressed, and regulated. | ||||||||||||
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課程目標 |
This course aims to provide basic knowledge in the field of molecular genetics, with emphasis on plant genetics. | ||||||||||||
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課程要求 |
Students' active in-class participation and at-home reading are required. | ||||||||||||
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 | ||||||||||||
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參考書目 |
- Craig NL, Cohen-Fix O, Green R, Greider CW, Storz G, Wolberger C (2014) Molecular Biology: Principles of Genome Function. 2nd edition Oxford Publisher (藝軒)
- Clark DP, Pazdernik NJ, McGehee MR (2018) Molecular Biology 3rd edition. Academic Cell. (可於台灣大學網域下載電子書：https://www.clinicalkey.com/#!/browse/book/3-s2.0-C20150062293，需於該網站免費註冊方能下載) - Griffiths AJF, Wessler SR, Carroll SB, Doebley J (2015) Introduction to Genetic Analysis. 11th edition. W.H. Freeman and Company. - Hartwell L, Goldberg ML, Fischer JA, Hood L (2017) Genetics: From Genes to Genomes. 6th edition. McGraw Hill Education (東華書局/新月圖書) - Krebs JE, Goldstien ES, Kilpatrick ST (2018) Lewin’s GENES XII, Jones and Bartlett Publisher. (合記) - Sanders MF and Bowman JL (2016) Genetic Analysis: An Integrated Approach. 2nd edition, Pearson (偉明) - Watson JD, Baker TA, Bell SP, Gann A, Levine M, and Losick R. (2013) Molecular Biology of the Gene 7th edition. Cold Spring Harbor Laboratory Press. (偉明) - 武村政春著，連程翔譯，張俊哲審訂，《世界第一簡單分子生物學》。台北：世茂出版有限公司，2011 。 本書為深入淺出，提供分生基本全貌之絕佳書籍！ | ||||||||||||
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評量方式 (僅供參考) |
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課程進度 |
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週次 |
日期 |
單元主題 |
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第1週 |
3/03 | Introduction to molecular genetics[Huang] |
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第2週 |
3/10 | DNA: structure and replication [Huang] |
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第3週 |
3/17 | RNA: transcription and processing [Huang] |
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第4週 |
3/24 | Protein and their synthesis [Huang] |
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第5週 |
3/31 | Mutation, repair, recombination (1/2) [Huang] |
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第6週 |
4/07 | Mutation, repair, recombination (2/2) [Huang] |
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第7週 |
4/14 | Large scale chromosome changes [Huang] |
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第8週 |
4/21 | Mid-term exam [Huang] |
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第9週 |
4/28 | Regulation of gene expression in prokaryotes [Lin] |
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第10週 |
5/05 | Regulation of gene expression in eukaryotes (1/2) [Lin] |
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第11週 |
5/12 | Regulation of gene expression in eukaryotes (2/2) [Lin] |
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第12週 |
5/19 | Recombinant DNA technology (1/2) [Lin] |
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第13週 |
5/26 | Recombinant DNA technology (2/2) [Lin] |
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第14週 |
6/02 | Forward and reverse genetics (1/2) [Lin] |
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第15週 |
6/09 | Forward and reverse genetics (2/2) [Lin] |
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第16週 |
6/16 | Final term exam [Lin] |
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第17週 |
6/23 | Plant developmental genetics [Lin] |
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第18週 |
6/30 | Overview of genomics [Huang] |